Angiotensinogen is Necessary for Postnatal Kidney Development • 1821
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چکیده
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The classical renin–angiotensin system (RAS) is activated by renin that is secreted from the juxtaglomerular cells of the afferent arteriole, which cleaves angiotensinogen (Agt), synthesized and released by the liver. This leads to the generation of a potent biologically active peptide, angiotensin II (AngII), which contributes to blood pressure regulation and sodium homeostasis. Recent studies...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1998
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199804001-01844